Radiation Oncology Protocols
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                                    Radiation Oncology Protocols                                                                                            Updated  4/10/08                                                                                                                                                                      (New Protocols in Red)                                                                                        RTOG Lead Investigator -- John Schallenkamp                                  jschallenkamp@billingsclinic.org

RTOG-Approved Treatment Sites                                                                                                    Billings Clinic                                                                                                                              Bozeman Cancer Center                                                                                                                   Great Falls Clinic                                                                                                                                 Sletten Cancer Center                                                                                                                      Welch Cancer Center-Sheridan, WY   (for information on site approval call Amanda at MCC or contact Dr. Schallenkamp)

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Future RTOG Meeting

June 19 -22, 2008

Contact Information

Montana Cancer Consortium 90 Poly Dr  Suite 2      Billings, MT  59101      Phone 406-259-2245      800-528-3340                 Fax  259-2682                Email mccinfo@mtcancer.org
 


 

Index

List by Protocol Number

Brain Gynecologic Lymphoma
Breast Head and Neck Melanoma
Gastrointestinal Leukemia Myeloma, Sarcoma, other
Genitourinary Lung Cancer Control

Cancer Control

RTOG R0518     Consent    HIPAA     Protocol   Supplemental Funding                                                                        Pre-registration requirements (see protocol section 5.0)

Phase III, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Zometa for the Prevention of Osteoporosis and Associated Fractures in Patients Receiving Radiation Therapy and Long-term LHRH Agonists for High-Grade and/or Locally Advanced Prostate Cancer 

RTOG R0517     Consent    HIPAA   Protocol                                                                                                                      Pre-registration requirements (see protocol section 5.0)

Randomized Phase III trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from Lung, Breast and Prostate Cancer

BRAIN

NCCTG RTOG 0525  Consent    HIPAA    Protocol

Phase II Trial Comparing Conventional Adjuvant Temozolomide with Dose-Intensive Temozolomide in Patients with Newly Diagnosed Glioblastoma

RTOG R0625  Consent   HIPAA     Protocol    Application    Information  (temporary closure)

A Randomized Phase II Trial of Bevacizumab with Irinotecan or Bevacizumab with Temozolomide in Recurrent Glioblastoma

       Brain Mets

NCCTG N0574  Consent   HIPAA    Protocol

Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases

BREAST

NSABP B-39        Consent    HIPAA    Fast Facts     Protocol    (Closed to specific patients)

A Randomized Phase III Study of Conventional Whole Breast Irradiation versus Partial Breast Irradiation for Women with Stage 0, I or II Breast Cancer

     Breast - Metastatic

RTOG R0517     Consent    HIPAA   Protocol                                                                                                                     Pre-registration requirements (see section 5.0 of the protocol)

Randomized Phase III trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from Lung, Breast and Prostate Cancer

GASTROINTESTINAL

  Colon - Rectal  

      Rectal

NSABP R-04    Consent    HIPAA     Fast Facts     Protocol

A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-Fluorouracil in the Treatment of Patients with Operable Carcinoma of the Rectum

CTSU E5204    Consent    HIPAA    Fast Facts    Protocol

Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin versus Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation

    Stomach

SWOG S0425     Consent     HIPAA    Fast Facts    Protocol

Neoadjuvant Chemoradiation Therapy with Oxaliplatin and Capecitabine for Patients with Surgically Resectable Gastric Cancer:  A Pilot Phase II Trial with Molecular Correlates

CTSU C80101  Consent   HIPAA     Fast Facts     Protocol

A Phase III Intergroup Trial of Adjuvant Chemoradiation after Resection of Gastric or Gastroesophageal Adenocarcinoma

    Esophageal

SWOG S0356    Consent      HIPAA      Protocol   

Oxaliplatin Plus Protracted Infusion 5-Fluorouracil and Radiation for Potentially Curable Esophageal Cancer:  A Phase II Trial with Molecular Correlates

    Pancreas

     Gallbladder

GENITOURINARY

    Prostate

CTSU MDA-3410    Consent    HIPAA    Fast Facts     Protocol  

A Prospective Randomized Phase II Trial Comparing Consolidation Therapy With or Without Strontium-89 Following Induction Chemotherapy in Androgen-Independent Prostate Cancer

CTSU RTOG 0415    Consent   HIPAA    Fast Facts    Protocol                                                                           Pre-registration requirements (see section 5.0 of the protocol)

A Phase III Randomized Study of Hypofractinated 3D-CRT/IMRT Versus Conventionally Fractionated 3D-CRT/IMRT in Patients with Favorable-Risk Prostate Cancer

CTSU RTOG 0521    Consent   Consent for Tissue   HIPAA      Protocol                                                  Pre-registration requirements (see section 5.0 of the protocol)

A Phase III Protocol of Androgen Suppression (AS) and Radiotherapy (RT) vs AS and RT Followed by Chemotherapy with Doxetaxel and Prednisone for Localized High-Risk Prostate Cancer

RTOG R0518     Consent    HIPAA     Protocol   Supplemental Funding                                                                 Pre-registration requirements (see section 5.0 of the protocol)

Phase III, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Zometa for the Prevention of Osteoporosis and Associated Fractures in Patients Receiving Radiation Therapy and Long-term LHRH Agonists for High-Grade and/or Locally Advanced Prostate Cancer 

RTOG R0517     Consent    HIPAA   Protocol                                                                                                               Pre-registration requirements (see section 5.0 of the protocol)

Randomized Phase III trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from Lung, Breast and Prostate Cancer

RTOG 0534  Consent     HIPAA     Protocol  

A Phase III Trial Of Short Term Androgen Deprivation With Pelvic Lymph Node Or Prostate Bed Only Radiotherapy (SPORT) In Prostate Cancer Patients With A Rising PSA After Radical Prostatectomy

    Bladder/Urothelium

    Germ Cell Malignancies

   Renal

GYNECOLOGIC

     Ovarian

    Cervical

CTSU GOG 0219    Consent    HIPAA    Fast Facts    Protocol

A Phase III Randomized Trial of Weekly Cisplatin and Radiotherapy versus Cisplatin and Tirapazamine and Radiotherapy in Stage IB2, IIA, IIIB, and IVA Cervical Cancer Limited to the Pelvis

    Endometrial

HEAD & NECK

CTSU RTOG 0522    Consent    HIPAA    Fast Facts    Protocol        PET Requirements and Credentialing

A Phase III Trial of Concurrent Accelerated Radiation and Chemotherapy vs Concurrent Accelerated Radiation, Chemotherapy and Cetuximab (C225) for Stage III and IV Head and Neck Carcinoma

RTOG R0435   Consent     HIPAA     Protocol    Training                                                                                           Pre-registration requirements (see section 5.0 of the protocol)

Randomized, Phase III, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Palifermin (NSC#740548m IND 6370) for the Reduction of Oral Mucositis in Patients with Locally-Advanced Head and Neck Cancer Receiving Radiation Therapy with concurrent Chemotherapy (Followed by surgery for Selected Patients) 

LEUKEMIA

    Acute Leukemia

    Chronic Leukemia

LUNG 

Non-Small Cell

SWOG S0429    Consent    HIPAA    Fast Facts    Protocol

A Pilot (Phase I) Study of Weekly Docetaxel and Cetuximab Chemoradiation for Poor Risk    Stage III Non-Small Cell Lung Cancer

NCCTG N0422    Consent    HIPAA     Protocol

Cetuximab and Radiation in Elderly and/or Poor Performance Status Patients with Locally Advanced Non-Small Cell Lung Cancer:  A Phase II Study to Evaluate Survival and Toxicity

RTOG R0517     Consent    HIPAA   Protocol                                                                                                               Pre-registration requirements (see section 5.0 of the protocol)

Randomized Phase III trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from Lung, Breast and Prostate Cancer

RTOG R0617     Consent     HIPAA     Protocol   

A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High-Dose (74 Gy) Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel in Patients With Stage IIIA/IIIB Non-Small Cell Lung Cancer

    Small Cell

RTOG R0623   Consent    HIPAA   Protocol  

A Phase II Trial of Combined Modality Therapy with Growth Factor Support for Patients with Limited Stage Small Cell Lung Cancer

LYMPHOMA

    Hodgkin's

   Non-Hodgkin's

SWOG 9704  Consent  HIPAA     Fast Facts    Protocol

A Randomized Phase III Trial Comparing Early High Dose Chemoradiotherapy and an Autologous Stem Cell Transplant to Conventional Dose CHOP Chemotherapy (With Possible Late Autologous Stem Cell Transplant) for Patients With Diffuse Aggressive Non-Hodgkin’s Lymphoma in the High-Intermediate and High Risk International Classification Prognostic Groups

    Mantle Cell

Melanoma                                                       

Myeloma

Sarcoma 

Other    

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