Primary Category:

Treatment Protocols

Disease Category:

Molecular Profiling



MATCH Treatment Subprotocol M: Phase II Study of MLN0128 (TAK-228) in Patients with Tumors with TSC1 or TSC2 Mutations

(See required screening study ECOG-ACRIN EAY131)

EAY131 Subprotocol M, is nearing completion of accrual goal.  Pending suspension with no remaining available slots effective July 22, 2021

Open  to participants with results from one of the designated outside laboratories indicating a “rare variant that is an actionable Mutation of Interest (aMOI) for specific designated rare variant subprotocols. See Appendix XIV of the main protocol for a list of the designated laboratories and applicable subprotocols.

The consent form for this sub-study is available upon request when a patient at your site is assigned to the sub-study.  Please contact Amber Boerner, or 406-969-6067, for the consent & for any questions.